SYNERGISTIC INDUCTION OF MITOTIC PYROPTOSIS AND TUMOR REMISSION BY INHIBITING PROTEASOME AND WEE FAMILY KINASES

Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

Abstract Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells.Whether pyroptosis can be a death form of MC remains unknown.Proteasome-mediated protein degradation is crucial for M-phase.Bortezomib (BTZ), which inhibits the 20S catalytic particle of proteasome, is ap

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Trends regarding Legal Profession Advertising

Legal advertising is the advertisement of legal services provided by a lawyer or a law firm to attract potential clients.The promotion and advertisement of legal services has undergone significant Cysteine transformation in recent years.The transition from the prohibition of such advertising to the current acceptance and utilization of online platf

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Anticounterfeit packaging technologies

Packaging is the coordinated system that encloses and protects the dosage form.copyright drugs are the major cause DC-DC Converters of morbidity, mortality, and failure of public interest in the healthcare system.High price and well-known brands make the pharma market most vulnerable, which accounts for top priority cardiovascular, obesity, and ant

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Contrasting environmental conditions precluded lower availability of Antarctic krill affecting breeding chinstrap penguins in the Antarctic Peninsula

Abstract Dramatic decreases of chinstrap penguin populations across the Antarctic Peninsula (AP) are thought to be influenced by climate-driven changes affecting its main prey, the Gas Filler Hose Antarctic krill, however, empirical evidence supporting such hypotheses are scarce.By coupling data on breeding chinstrap penguins, environmental remote

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